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Your Position: Home > IL-1 alpha

IL-1 alpha

Brief Information

Name:Interleukin-1 alpha
Target Synonym:Interleukin-1 Alpha,IL1A,IL1F1,IL-1 alpha,Interleukin 1 Alpha,Hematopoietin-1,Pro-Interleukin-1-Alpha,Preinterleukin 1 Alpha,IL1-ALPHA,IL-1A,IL1,Interleukin-1alpha
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:7
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
ILA-H5214 Human Human IL-1 alpha / IL-1F1 Protein, premium grade
ILA-H5214-structure
ILA-H5214-sds
ILA-M82E8 Mouse Biotinylated Mouse IL-1 alpha / IL-1F1 Protein, His,Avitag™ (MALS verified)
ILA-M82E8-structure
ILA-M82E8-sds
ILA-H82E7 Human Biotinylated Human IL-1 alpha / IL-1F1 Protein, His,Avitag™ (MALS verified)
ILA-H82E7-structure
ILA-H82E7-sds
ILA-M5213 Mouse Mouse IL-1 alpha / IL-1F1 Protein, His Tag (MALS verified)
ILA-M5213-structure
ILA-M5213-sds
ILA-H5216 Human Human IL-1 alpha / IL-1F1 Protein, His Tag (MALS verified)
ILA-H5216-structure
ILA-H5216-sds
ACRO Quality

Part of Bioactivity data

ILA-H5216-ELISA
IL-1 alpha ELISA

Immobilized Human IL-1 RI Protein, Fc Tag (Cat. No. ILI-H5253) at 10 μg/mL (100 μL/well) can bind Human IL-1 alpha, His Tag (Cat. No. ILA-H5216) with a linear range of 0.3-2.5 μg/mL (QC tested).

Protocol
ILA-M82E8-MALS-HPLC
Biotinylated Mouse IL-1 alpha, His,Avitag (Cat. No. ) MALS images

The purity of Biotinylated Mouse IL-1 alpha, His,Avitag (Cat. No. ILA-M82E8) is more than 90% and the molecular weight of this protein is around 21-31kDa verified by SEC-MALS.

Report
  • Background
    Interleukin-1 alpha (IL1a) is also known as IL-1A, IL1, IL1-ALPHA,IL1F1,and is a cytokine of the interleukin-1 family. IL1a possesses a wide spectrum of metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. IL-1α is constitutively produced by epithelial cells. It is found in substantial amounts in normal human epidermis and is distributed in a 1:1 ratio between living epidermal cells and stratum corneum.The constitutive production of large amounts of IL-1α precursor by healthy epidermal keratinocytes interfere with the important role of IL-1α in immune responses, assuming skin as a barrier, which prevents the entry of pathogenic microorganisms into the body. In vitro, IL-1α possesses biological effect on cells in the picomolar to femtomolar range. In vivo, Shortly after an onset of an infection into organism, IL-1α activates a set of immune system response processes.
  • Clinical and Translational Updates
      

  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

Synonym Name

IL1A,IL-1 ALPHA,IL1F1,IL1α

Background

Interleukin-1 alpha (IL1a) is also known as  IL-1A, IL1, IL1-ALPHA,IL1F1,and is a cytokine of the interleukin-1 family. IL1a possesses a wide spectrum of metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. IL-1α is constitutively produced by epithelial cells. It is found in substantial amounts in normal human epidermis and is distributed in a 1:1 ratio between living epidermal cells and stratum corneum.The constitutive production of large amounts of IL-1α precursor by healthy epidermal keratinocytes interfere with the important role of IL-1α in immune responses, assuming skin as a barrier, which prevents the entry of pathogenic microorganisms into the body. In vitro, IL-1α possesses biological effect on cells in the picomolar to femtomolar range. In vivo, Shortly after an onset of an infection into organism, IL-1α activates a set of immune system response processes.

Clinical and Translational Updates

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